69
2700:Medicine(比率: 43.2 %)
| DOI | タイトル | 著者 | ジャーナル | 発行年 | 科研費成果論文 |
|---|---|---|---|---|---|
| 10.1007/s00262-018-2281-2 | Crispr/Cas9-Mediated Pd-1 Disruption Enhances Human Mesothelin-Targeted Car T Cell Effector Functions | Hu, Wanghong; Zi, Zhenguo; Jin, Yanling; Li, Gaoxin; Shao, Kang; Cai, Qiliang; Ma, Xiaojing; Wei, Fang, 0000-0001-8964-1645 | Cancer Immunology, Immunotherapy | 2018 | NA |
| 10.1016/j.cell.2018.05.060 | Single-Cell Map Of Diverse Immune Phenotypes In The Breast Tumor Microenvironment | Cell | 2018 | NA | |
| 10.1016/j.cell.2018.09.006 | A Cancer Cell Program Promotes T Cell Exclusion And Resistance To Checkpoint Blockade | Jerby-Arnon, Livnat; Shah, Parin; Cuoco, Michael S.; Rodman, Christopher; Su, Mei-Ju; Melms, Johannes C.; Leeson, Rachel; Kanodia, Abhay; Mei, Shaolin; Lin, Jia-Ren; Wang, Shu; Rabasha, Bokang; Liu, David; Zhang, Gao; Margolais, Claire; Ashenberg, Orr; Ott, Patrick A.; Buchbinder, Elizabeth I.; Haq, Rizwan; Hodi, F. Stephen; Boland, Genevieve M.; Sullivan, Ryan J.; Frederick, Dennie T.; Miao, Benchun; Moll, Tabea; Flaherty, Keith T.; Herlyn, Meenhard; Jenkins, Russell W.; Thummalapalli, Rohit; Kowalczyk, Monika S.; Canadas, Israel; Schilling, Bastian; Cartwright, Adam N.R.; Luoma, Adrienne M.; Malu, Shruti; Hwu, Patrick; Bernatchez, Chantale; Forget, Marie-Andree; Barbie, David A.; Shalek, Alex K.; Tirosh, Itay; Sorger, Peter K.; Wucherpfennig, Kai; Van Allen, Eliezer M.; Schadendorf, Dirk; Johnson, Bruce E.; Rotem, Asaf; Rozenblatt-Rosen, Orit; Garraway, Levi A.; Yoon, Charles H.; Izar, Benjamin; Regev, Aviv | Cell | 2018 | NA |
| 10.1016/j.cell.2018.10.038 | Defining T Cell States Associated With Response To Checkpoint Immunotherapy In Melanoma | Sade-Feldman, Moshe; Yizhak, Keren; Bjorgaard, Stacey L.; Ray, John P.; De Boer, Carl G.; Jenkins, Russell W.; Lieb, David J.; Chen, Jonathan H.; Frederick, Dennie T.; Barzily-Rokni, Michal; Freeman, Samuel S.; Reuben, Alexandre; Hoover, Paul J.; Villani, Alexandra-Chloe; Ivanova, Elena; Portell, Andrew; Lizotte, Patrick H.; Aref, Amir R.; Eliane, Jean-Pierre; Hammond, Marc R.; Vitzthum, Hans; Blackmon, Shauna M.; Li, Bo; Gopalakrishnan, Vancheswaran; Reddy, Sangeetha M.; Cooper, Zachary A.; Paweletz, Cloud P.; Barbie, David A.; Stemmer-Rachamimov, Anat; Flaherty, Keith T.; Wargo, Jennifer A.; Boland, Genevieve M.; Sullivan, Ryan J.; Getz, Gad; Hacohen, Nir | Cell | 2018 | NA |
| 10.1016/j.cell.2018.11.043 | Dysfunctional Cd8 T Cells Form A Proliferative, Dynamically Regulated Compartment Within Human Melanoma | Li, Hanjie; Van Der Leun, Anne M.; Yofe, Ido; Lubling, Yaniv; Gelbard-Solodkin, Dikla; Van Akkooi, Alexander C.J.; Van Den Braber, Marlous; Rozeman, Elisa A.; Haanen, John B.A.G.; Blank, Christian U.; Horlings, Hugo M.; David, Eyal; Baran, Yael; Bercovich, Akhiad; Lifshitz, Aviezer; Schumacher, Ton N.; Tanay, Amos; Amit, Ido | Cell | 2019 | NA |
| 10.1016/j.cell.2019.07.032 | Effector Th17 Cells Give Rise To Long-Lived Trm Cells That Are Essential For An Immediate Response Against Bacterial Infection | Amezcua Vesely, Maria Carolina; Pallis, Paris; Bielecki, Piotr; Low, Jun Siong; Zhao, Jun; Harman, Christian C.D.; Kroehling, Lina; Jackson, Ruaidhri; Bailis, Will; Licona-Limon, Paula; Xu, Hao; Iijima, Norifumi; Pillai, Padmini S.; Kaplan, Daniel H.; Weaver, Casey T.; Kluger, Yuval; Kowalczyk, Monika S.; Iwasaki, Akiko; Pereira, Joao P.; Esplugues, Enric; Gagliani, Nicola; Flavell, Richard A. | Cell | 2019 | TRUE |
| 10.1016/j.immuni.2018.11.014 | Kurtulus, Sema; Madi, Asaf; Escobar, Giulia; Klapholz, Max; Nyman, Jackson; Christian, Elena; Pawlak, Mathias; Dionne, Danielle; Xia, Junrong; Rozenblatt-Rosen, Orit; Kuchroo, Vijay K.; Regev, Aviv; Anderson, Ana C. | Immunity | 2019 | NA | |
| 10.1016/j.immuni.2018.12.021 | Intratumoral Tcf1+Pd-1+Cd8+ T Cells With Stem-Like Properties Promote Tumor Control In Response To Vaccination And Checkpoint Blockade Immunotherapy | Siddiqui, Imran; Schaeuble, Karin; Chennupati, Vijaykumar; Fuertes Marraco, Silvia A.; Calderon-Copete, Sandra; Pais Ferreira, Daniela; Carmona, Santiago J.; Scarpellino, Leonardo; Gfeller, David; Pradervand, Sylvain; Luther, Sanjiv A.; Speiser, Daniel E.; Held, Werner | Immunity | 2019 | NA |
| 10.1016/j.immuni.2019.09.013 | Tcf-1-Centered Transcriptional Network Drives An Effector Versus Exhausted Cd8 T Cell-Fate Decision | Chen, Zeyu; Ji, Zhicheng; Ngiow, Shin Foong; Manne, Sasikanth; Cai, Zhangying; Huang, Alexander C.; Johnson, John; Staupe, Ryan P.; Bengsch, Bertram; Xu, Caiyue; Yu, Sixiang; Kurachi, Makoto; Herati, Ramin S.; Vella, Laura A.; Baxter, Amy E.; Wu, Jennifer E.; Khan, Omar; Beltra, Jean-Christophe; Giles, Josephine R.; Stelekati, Erietta; Mclane, Laura M.; Lau, Chi Wai; Yang, Xiaolu; Berger, Shelley L.; Vahedi, Golnaz; Ji, Hongkai; Wherry, E. John | Immunity | 2019 | TRUE |
| 10.1016/j.immuni.2019.10.009 | Cd4+ T Cell Help Is Required For The Formation Of A Cytolytic Cd8+ T Cell Subset That Protects Against Chronic Infection And Cancer | Zander, Ryan; Schauder, David; Xin, Gang; Nguyen, Christine; Wu, Xiaopeng; Zajac, Allan; Cui, Weiguo, 0000-0003-1562-9218 | Immunity | 2019 | NA |
| 10.1016/j.immuni.2019.11.002 | Proliferating Transitory T Cells With An Effector-Like Transcriptional Signature Emerge From Pd-1+ Stem-Like Cd8+ T Cells During Chronic Infection | Hudson, William H.; Gensheimer, Julia; Hashimoto, Masao; Wieland, Andreas; Valanparambil, Rajesh M.; Li, Peng; Lin, Jian-Xin; Konieczny, Bogumila T.; Im, Se Jin; Freeman, Gordon J.; Leonard, Warren J.; Kissick, Haydn T.; Ahmed, Rafi | Immunity | 2019 | NA |
| 10.1016/j.immuni.2020.04.007 | Heterogenous Populations Of Tissue-Resident Cd8+ T Cells Are Generated In Response To Infection And Malignancy | Milner, J. Justin; Toma, Clara; He, Zhaoren; Kurd, Nadia S.; Nguyen, Quynh P.; Mcdonald, Bryan; Quezada, Lauren; Widjaja, Christella E.; Witherden, Deborah A.; Crowl, John T.; Shaw, Laura A.; Yeo, Gene W.; Chang, John T.; Omilusik, Kyla D.; Goldrath, Ananda W. | Immunity | 2020 | NA |
| 10.1016/j.immuni.2020.04.014 | Developmental Relationships Of Four Exhausted Cd8+ T Cell Subsets Reveals Underlying Transcriptional And Epigenetic Landscape Control Mechanisms | Beltra, Jean-Christophe; Manne, Sasikanth; Abdel-Hakeem, Mohamed S.; Kurachi, Makoto; Giles, Josephine R.; Chen, Zeyu; Casella, Valentina; Ngiow, Shin Foong; Khan, Omar; Huang, Yinghui Jane; Yan, Patrick; Nzingha, Kito; Xu, Wei; Amaravadi, Ravi K.; Xu, Xiaowei; Karakousis, Giorgos C.; Mitchell, Tara C.; Schuchter, Lynn M.; Huang, Alexander C.; Wherry, E. John | Immunity | 2020 | TRUE |
| 10.1016/j.it.2019.06.002 | Tissue-Resident Memory T Cells In Cancer Immunosurveillance | Park, Simone L.; Gebhardt, Thomas; Mackay, Laura K. | Trends In Immunology | 2019 | NA |
| 10.1016/j.jhep.2019.05.015 | Tox Promotes The Exhaustion Of Antitumor Cd8+ T Cells By Preventing Pd1 Degradation In Hepatocellular Carcinoma | Wang, Xiaochen; He, Qifeng; Shen, Haiyuan; Xia, Anliang; Tian, Wenfang; Yu, Weiwei; Sun, Beicheng, 0000-0002-3795-4153 | Journal Of Hepatology | 2019 | NA |
| 10.1016/j.omto.2018.10.006 | Preclinical Development Of Bivalent Chimeric Antigen Receptors Targeting Both Cd19 And Cd22 | Qin, Haiying; Ramakrishna, Sneha; Nguyen, Sang; Fountaine, Thomas J.; Ponduri, Anusha; Stetler-Stevenson, Maryalice; Yuan, Constance M.; Haso, Waleed; Shern, Jack F.; Shah, Nirali N.; Fry, Terry J. | Molecular Therapy - Oncolytics | 2018 | NA |
| 10.1038/s41467-018-05072-0 | Co-Expression Of Cd39 And Cd103 Identifies Tumor-Reactive Cd8 T Cells In Human Solid Tumors | Duhen, Thomas; Duhen, Rebekka; Montler, Ryan; Moses, Jake; Moudgil, Tarsem; De Miranda, Noel F.; Goodall, Cheri P.; Blair, Tiffany C.; Fox, Bernard A.; Mcdermott, Jason E., 0000-0003-2961-2572; Chang, Shu-Ching; Grunkemeier, Gary; Leidner, Rom; Bell, Richard Bryan; Weinberg, Andrew D. | Nature Communications | 2018 | NA |
| 10.1038/s41467-019-12319-x | Tissue-Resident Memory Cd8+ T Cells Amplify Anti-Tumor Immunity By Triggering Antigen Spreading Through Dendritic Cells | Menares, Evelyn, 0000-0001-9156-1660; Galvez-Cancino, Felipe, 0000-0001-8417-1891; Caceres-Morgado, Pablo, 0000-0002-9199-923X; Ghorani, Ehsan, 0000-0001-5373-5762; Lopez, Ernesto; Diaz, Ximena, 0000-0001-9036-4868; Saavedra-Almarza, Juan, 0000-0002-2329-6284; Figueroa, Diego A., 0000-0002-7003-9205; Roa, Eduardo, 0000-0002-0594-4719; Quezada, Sergio A., 0000-0002-9763-1700; Lladser, Alvaro, 0000-0002-5576-1478 | Nature Communications | 2019 | NA |
| 10.1038/s41577-019-0221-9 | Blank, Christian U., 0000-0002-7945-5846; Haining, W. Nicholas; Held, Werner, 0000-0003-3292-1536; Hogan, Patrick G., 0000-0001-9869-0684; Kallies, Axel, 0000-0002-6312-6968; Lugli, Enrico, 0000-0002-1964-7678; Lynn, Rachel C., 0000-0002-0489-8634; Philip, Mary, 0000-0001-7496-2630; Rao, Anjana; Restifo, Nicholas P.; Schietinger, Andrea, 0000-0003-3644-1687; Schumacher, Ton N., 0000-0003-0517-8804; Schwartzberg, Pamela L., 0000-0001-6318-9187; Sharpe, Arlene H., 0000-0002-9736-2109; Speiser, Daniel E., 0000-0003-2031-3250; Wherry, E. John, 0000-0003-0477-1956; Youngblood, Benjamin A., 0000-0002-1261-9957; Zehn, Dietmar, 0000-0003-1393-8527 | Nature Reviews Immunology | 2019 | NA | |
| 10.1038/s41577-019-0223-7 | Precursor Exhausted T Cells: Key To Successful Immunotherapy? | Kallies, Axel, 0000-0002-6312-6968; Zehn, Dietmar, 0000-0003-1393-8527; Utzschneider, Daniel T. | Nature Reviews Immunology | 2019 | NA |
| 10.1038/s41586-018-0130-2 | Bystander Cd8+ T Cells Are Abundant And Phenotypically Distinct In Human Tumour Infiltrates | Simoni, Yannick; Becht, Etienne; Fehlings, Michael; Loh, Chiew Yee; Koo, Si-Lin; Teng, Karen Wei Weng; Yeong, Joe Poh Sheng; Nahar, Rahul; Zhang, Tong; Kared, Hassen; Duan, Kaibo; Ang, Nicholas; Poidinger, Michael; Lee, Yin Yeng; Larbi, Anis; Khng, Alexis J.; Tan, Emile; Fu, Cherylin; Mathew, Ronnie; Teo, Melissa; Lim, Wan Teck; Toh, Chee Keong; Ong, Boon-Hean; Koh, Tina; Hillmer, Axel M.; Takano, Angela; Lim, Tony Kiat Hon; Tan, Eng Huat; Zhai, Weiwei; Tan, Daniel S. W.; Tan, Iain Beehuat; Newell, Evan W. | Nature | 2018 | NA |
| 10.1038/s41586-018-0694-x | Lineage Tracking Reveals Dynamic Relationships Of T Cells In Colorectal Cancer | Zhang, Lei; Yu, Xin; Zheng, Liangtao; Zhang, Yuanyuan; Li, Yansen; Fang, Qiao; Gao, Ranran; Kang, Boxi; Zhang, Qiming; Huang, Julie Y.; Konno, Hiroyasu; Guo, Xinyi; Ye, Yingjiang; Gao, Songyuan; Wang, Shan; Hu, Xueda; Ren, Xianwen; Shen, Zhanlong; Ouyang, Wenjun; Zhang, Zemin | Nature | 2018 | NA |
| 10.1038/s41586-018-0812-9 | Tissue-Resident Memory Cd8+ T Cells Promote Melanoma<U+2013>Immune Equilibrium In Skin | Park, Simone L.; Buzzai, Anthony; Rautela, Jai; Hor, Jyh Liang; Hochheiser, Katharina; Effern, Maike; Mcbain, Nathan; Wagner, Teagan; Edwards, Jarem; Mcconville, Robyn; Wilmott, James S.; Scolyer, Richard A.; Tuting, Thomas; Palendira, Umaimainthan; Gyorki, David; Mueller, Scott N.; Huntington, Nicholas D.; Bedoui, Sammy; Holzel, Michael; Mackay, Laura K.; Waithman, Jason; Gebhardt, Thomas | Nature | 2018 | NA |
| 10.1038/s41586-019-0979-8 | Genome-Wide Analysis Identifies Nr4A1 As A Key Mediator Of T Cell Dysfunction | Liu, Xindong; Wang, Yun; Lu, Huiping; Li, Jing; Yan, Xiaowei; Xiao, Minglu; Hao, Jing; Alekseev, Andrei; Khong, Hiep; Chen, Tenghui; Huang, Rui; Wu, Jin; Zhao, Qiwen; Wu, Qi; Xu, Senlin; Wang, Xiaohu; Jin, Wei; Yu, Shicang; Wang, Yan; Wei, Lai; Wang, Aibo; Zhong, Bo; Ni, Ling; Liu, Xiaolong; Nurieva, Roza; Ye, Lilin; Tian, Qiang; Bian, Xiu-Wu; Dong, Chen | Nature | 2019 | NA |
| 10.1038/s41586-019-0985-x | Nr4A Transcription Factors Limit Car T Cell Function In Solid Tumours | Chen, Joyce; Lopez-Moyado, Isaac F.; Seo, Hyungseok; Lio, Chan-Wang J.; Hempleman, Laura J.; Sekiya, Takashi; Yoshimura, Akihiko; Scott-Browne, James P.; Rao, Anjana | Nature | 2019 | TRUE |
| 10.1038/s41586-019-1054-1 | Car T Cell Trogocytosis And Cooperative Killing Regulate Tumour Antigen Escape | Hamieh, Mohamad; Dobrin, Anton; Cabriolu, Annalisa; Van Der Stegen, Sjoukje J. C.; Giavridis, Theodoros; Mansilla-Soto, Jorge; Eyquem, Justin; Zhao, Zeguo; Whitlock, Benjamin M.; Miele, Matthew M.; Li, Zhuoning; Cunanan, Kristen M.; Huse, Morgan; Hendrickson, Ronald C.; Wang, Xiuyan; Riviere, Isabelle; Sadelain, Michel | Nature | 2019 | NA |
| 10.1038/s41586-019-1324-y | Tox Is A Critical Regulator Of Tumour-Specific T Cell Differentiation | Scott, Andrew C.; Dundar, Friederike; Zumbo, Paul; Chandran, Smita S.; Klebanoff, Christopher A.; Shakiba, Mojdeh; Trivedi, Prerak; Menocal, Laura; Appleby, Heather; Camara, Steven; Zamarin, Dmitriy; Walther, Tyler; Snyder, Alexandra; Femia, Matthew R.; Comen, Elizabeth A.; Wen, Hannah Y.; Hellmann, Matthew D.; Anandasabapathy, Niroshana; Liu, Yong; Altorki, Nasser K.; Lauer, Peter; Levy, Olivier; Glickman, Michael S.; Kaye, Jonathan; Betel, Doron; Philip, Mary; Schietinger, Andrea | Nature | 2019 | NA |
| 10.1038/s41586-019-1325-x | Tox Transcriptionally And Epigenetically Programs Cd8+ T Cell Exhaustion | Khan, Omar; Giles, Josephine R.; Mcdonald, Sierra; Manne, Sasikanth; Ngiow, Shin Foong; Patel, Kunal P.; Werner, Michael T.; Huang, Alexander C.; Alexander, Katherine A.; Wu, Jennifer E.; Attanasio, John; Yan, Patrick; George, Sangeeth M.; Bengsch, Bertram; Staupe, Ryan P.; Donahue, Greg; Xu, Wei; Amaravadi, Ravi K.; Xu, Xiaowei; Karakousis, Giorgos C.; Mitchell, Tara C.; Schuchter, Lynn M.; Kaye, Jonathan; Berger, Shelley L.; Wherry, E. John | Nature | 2019 | NA |
| 10.1038/s41586-019-1326-9 | Tox Reinforces The Phenotype And Longevity Of Exhausted T Cells In Chronic Viral Infection | Alfei, Francesca; Kanev, Kristiyan; Hofmann, Maike; Wu, Ming; Ghoneim, Hazem E.; Roelli, Patrick; Utzschneider, Daniel T.; Von Hoesslin, Madlaina; Cullen, Jolie G.; Fan, Yiping; Eisenberg, Vasyl; Wohlleber, Dirk; Steiger, Katja; Merkler, Doron; Delorenzi, Mauro; Knolle, Percy A.; Cohen, Cyrille J.; Thimme, Robert; Youngblood, Benjamin; Zehn, Dietmar | Nature | 2019 | NA |
| 10.1038/s41586-019-1805-z | C-Jun Overexpression In Car T Cells Induces Exhaustion Resistance | Lynn, Rachel C.; Weber, Evan W.; Sotillo, Elena; Gennert, David; Xu, Peng; Good, Zinaida; Anbunathan, Hima; Lattin, John; Jones, Robert; Tieu, Victor; Nagaraja, Surya; Granja, Jeffrey; De Bourcy, Charles F. A.; Majzner, Robbie; Satpathy, Ansuman T.; Quake, Stephen R.; Monje, Michelle; Chang, Howard Y.; Mackall, Crystal L. | Nature | 2019 | NA |
| 10.1038/s41586-019-1836-5 | An Intra-Tumoral Niche Maintains And Differentiates Stem-Like Cd8 T Cells | Jansen, Caroline S.; Prokhnevska, Nataliya; Master, Viraj A.; Sanda, Martin G.; Carlisle, Jennifer W.; Bilen, Mehmet Asim; Cardenas, Maria; Wilkinson, Scott; Lake, Ross; Sowalsky, Adam G.; Valanparambil, Rajesh M.; Hudson, William H.; Mcguire, Donald; Melnick, Kevin; Khan, Amir I.; Kim, Kyu; Chang, Yun Min; Kim, Alice; Filson, Christopher P.; Alemozaffar, Mehrdad; Osunkoya, Adeboye O.; Mullane, Patrick; Ellis, Carla; Akondy, Rama; Im, Se Jin; Kamphorst, Alice O.; Reyes, Adriana; Liu, Yuan; Kissick, Haydn | Nature | 2019 | NA |
| 10.1038/s41586-020-2056-8 | Peripheral T Cell Expansion Predicts Tumour Infiltration And Clinical Response | Nature | 2020 | NA | |
| 10.1038/s41590-019-0312-6 | Subsets Of Exhausted Cd8+ T Cells Differentially Mediate Tumor Control And Respond To Checkpoint Blockade | Miller, Brian C., 0000-0001-5931-4184; Sen, Debattama R., 0000-0002-0947-8284; Al Abosy, Rose, 0000-0001-5400-1306; Bi, Kevin; Virkud, Yamini V.; Lafleur, Martin W., 0000-0002-5017-774X; Yates, Kathleen B.; Lako, Ana; Felt, Kristen; Naik, Girish S.; Manos, Michael; Gjini, Evisa; Kuchroo, Juhi R.; Ishizuka, Jeffrey J.; Collier, Jenna L., 0000-0002-4071-4986; Griffin, Gabriel K.; Maleri, Seth; Comstock, Dawn E.; Weiss, Sarah A.; Brown, Flavian D.; Panda, Arpit; Zimmer, Margaret D.; Manguso, Robert T.; Hodi, F. Stephen; Rodig, Scott J.; Sharpe, Arlene H.; Haining, W. Nicholas, 0000-0001-7871-3762 | Nature Immunology | 2019 | NA |
| 10.1038/s41590-019-0403-4 | Single-Cell Rna-Seq Reveals Tox As A Key Regulator Of Cd8+ T Cell Persistence In Chronic Infection | Nature Immunology | 2019 | NA | |
| 10.1038/s41590-020-0607-7 | Developmental Plasticity Allows Outside-In Immune Responses By Resident Memory T Cells | Fonseca, Raissa, 0000-0001-8202-4871; Beura, Lalit K., 0000-0002-8597-3949; Quarnstrom, Clare F.; Ghoneim, Hazem E., 0000-0002-9816-4286; Fan, Yiping; Zebley, Caitlin C.; Scott, Milcah C., 0000-0003-2151-7335; Fares-Frederickson, Nancy J.; Wijeyesinghe, Sathi, 0000-0002-8819-2654; Thompson, Emily A.; Borges Da Silva, Henrique; Vezys, Vaiva; Youngblood, Benjamin; Masopust, David, 0000-0002-9440-3884 | Nature Immunology | 2020 | NA |
| 10.1038/s41591-018-0045-3 | Global Characterization Of T Cells In Non-Small-Cell Lung Cancer By Single-Cell Sequencing | Guo, Xinyi; Zhang, Yuanyuan; Zheng, Liangtao; Zheng, Chunhong; Song, Jintao; Zhang, Qiming; Kang, Boxi; Liu, Zhouzerui; Jin, Liang; Xing, Rui; Gao, Ranran; Zhang, Lei; Dong, Minghui; Hu, Xueda; Ren, Xianwen, 0000-0002-8558-5401; Kirchhoff, Dennis; Roider, Helge Gottfried; Yan, Tiansheng; Zhang, Zemin, 0000-0003-3789-6536 | Nature Medicine | 2018 | NA |
| 10.1038/s41591-018-0078-7 | Single-Cell Profiling Of Breast Cancer T Cells Reveals A Tissue-Resident Memory Subset Associated With Improved Prognosis | Savas, Peter, 0000-0001-5999-428X; Virassamy, Balaji; Ye, Chengzhong; Salim, Agus; Mintoff, Christopher P.; Caramia, Franco; Salgado, Roberto; Byrne, David J.; Teo, Zhi L.; Dushyanthen, Sathana; Byrne, Ann; Wein, Lironne; Luen, Stephen J.; Poliness, Catherine; Nightingale, Sophie S.; Skandarajah, Anita S.; Gyorki, David E.; Thornton, Chantel M.; Beavis, Paul A.; Fox, Stephen B., 0000-0002-7648-8896; Darcy, Phillip K.; Speed, Terence P.; Mackay, Laura K., 0000-0002-8496-6632; Neeson, Paul J.; Loi, Sherene, 0000-0001-6137-9171 | Nature Medicine | 2018 | NA |
| 10.1038/s41591-018-0096-5 | Phenotype Molding Of Stromal Cells In The Lung Tumor Microenvironment | Lambrechts, Diether, 0000-0002-3429-302X; Wauters, Els; Boeckx, Bram; Aibar, Sara, 0000-0001-6104-7134; Nittner, David; Burton, Oliver; Bassez, Ayse; Decaluwe, Herbert, 0000-0002-0877-7717; Pircher, Andreas; Van Den Eynde, Kathleen; Weynand, Birgit, 0000-0003-4246-6303; Verbeken, Erik; De Leyn, Paul; Liston, Adrian, 0000-0002-6272-4085; Vansteenkiste, Johan, 0000-0002-6721-2775; Carmeliet, Peter; Aerts, Stein; Thienpont, Bernard, 0000-0002-8772-6845 | Nature Medicine | 2018 | NA |
| 10.1038/s41591-018-0146-z | Genetic Mechanisms Of Target Antigen Loss In Car19 Therapy Of Acute Lymphoblastic Leukemia | Orlando, Elena J.; Han, Xia; Tribouley, Catherine; Wood, Patricia A.; Leary, Rebecca J.; Riester, Markus, 0000-0002-4759-8332; Levine, John E.; Qayed, Muna; Grupp, Stephan A.; Boyer, Michael; De Moerloose, Barbara; Nemecek, Eneida R.; Bittencourt, Henrique; Hiramatsu, Hidefumi; Buechner, Jochen; Davies, Stella M.; Verneris, Michael R.; Nguyen, Kevin; Brogdon, Jennifer L.; Bitter, Hans; Morrissey, Michael; Pierog, Piotr, 0000-0001-6711-4107; Pantano, Serafino; Engelman, Jeffrey A.; Winckler, Wendy | Nature Medicine | 2018 | NA |
| 10.1038/s41591-018-0201-9 | Induction Of Resistance To Chimeric Antigen Receptor T Cell Therapy By Transduction Of A Single Leukemic B Cell | Ruella, Marco, 0000-0003-4301-5811; Xu, Jun; Barrett, David M.; Fraietta, Joseph A.; Reich, Tyler J., 0000-0003-0178-1411; Ambrose, David E.; Klichinsky, Michael; Shestova, Olga; Patel, Prachi R.; Kulikovskaya, Irina; Nazimuddin, Farzana; Bhoj, Vijay G.; Orlando, Elena J.; Fry, Terry J., 0000-0001-8044-5226; Bitter, Hans; Maude, Shannon L.; Levine, Bruce L., 0000-0001-6971-8465; Nobles, Christopher L.; Bushman, Frederic D.; Young, Regina M.; Scholler, John; Gill, Saar I.; June, Carl H., 0000-0003-0241-3557; Grupp, Stephan A.; Lacey, Simon F.; Melenhorst, J. Joseph | Nature Medicine | 2018 | NA |
| 10.1038/s41591-018-0266-5 | Low And Variable Tumor Reactivity Of The Intratumoral Tcr Repertoire In Human Cancers | Scheper, Wouter; Kelderman, Sander; Fanchi, Lorenzo F.; Linnemann, Carsten; Bendle, Gavin; De Rooij, Marije A. J.; Hirt, Christian; Mezzadra, Riccardo; Slagter, Maarten; Dijkstra, Krijn; Kluin, Roelof J. C.; Snaebjornsson, Petur, 0000-0002-1086-8108; Milne, Katy; Nelson, Brad H.; Zijlmans, Henry; Kenter, Gemma; Voest, Emile E.; Haanen, John B. A. G., 0000-0001-5884-7704; Schumacher, Ton N., 0000-0003-0517-8804 | Nature Medicine | 2018 | NA |
| 10.1038/s41591-018-0290-5 | Calibration Of Car Activation Potential Directs Alternative T Cell Fates And Therapeutic Potency | Feucht, Judith; Sun, Jie; Eyquem, Justin; Ho, Yu-Jui; Zhao, Zeguo; Leibold, Josef; Dobrin, Anton; Cabriolu, Annalisa; Hamieh, Mohamad; Sadelain, Michel, 0000-0002-9031-8025 | Nature Medicine | 2018 | NA |
| 10.1038/s41591-019-0421-7 | A Safe And Potent Anti-Cd19 Car T Cell Therapy | Ying, Zhitao; Huang, Xue F.; Xiang, Xiaoyu; Liu, Yanling; Kang, Xi; Song, Yuqin; Guo, Xiaokai; Liu, Hanzhi; Ding, Ning; Zhang, Tingting; Duan, Panpan; Lin, Yufu; Zheng, Wen; Wang, Xiaopei; Lin, Ningjing; Tu, Meifeng; Xie, Yan; Zhang, Chen; Liu, Weiping; Deng, Lijuan; Gao, Shunyu; Ping, Lingyan; Wang, Xuejuan; Zhou, Nina; Zhang, Junqing; Wang, Yulong; Lin, Songfeng; Mamuti, Mierzhati; Yu, Xueyun; Fang, Lizhu; Wang, Shuai; Song, Haifeng; Wang, Guan; Jones, Lindsey; Zhu, Jun, 0000-0003-3479-2547; Chen, Si-Yi, 0000-0003-2403-4988 | Nature Medicine | 2019 | NA |
| 10.1038/s41591-019-0522-3 | Clonal Replacement Of Tumor-Specific T Cells Following Pd-1 Blockade | Yost, Kathryn E.; Satpathy, Ansuman T., 0000-0002-5167-537X; Wells, Daniel K.; Qi, Yanyan; Wang, Chunlin; Kageyama, Robin; Mcnamara, Katherine L.; Granja, Jeffrey M.; Sarin, Kavita Y., 0000-0001-5363-3053; Brown, Ryanne A.; Gupta, Rohit K.; Curtis, Christina, 0000-0003-0166-3802; Bucktrout, Samantha L.; Davis, Mark M., 0000-0001-6868-657X; Chang, Anne Lynn S., 0000-0002-2869-2147; Chang, Howard Y., 0000-0002-9459-4393 | Nature Medicine | 2019 | NA |
| 10.1038/s41591-019-0549-5 | Enhanced Car T Cell Expansion And Prolonged Persistence In Pediatric Patients With All Treated With A Low-Affinity Cd19 Car | Ghorashian, Sara, 0000-0002-1555-2946; Kramer, Anne Marijn; Onuoha, Shimobi; Wright, Gary; Bartram, Jack; Richardson, Rachel; Albon, Sarah J.; Casanovas-Company, Joan; Castro, Fernanda; Popova, Bilyana; Villanueva, Krystle; Yeung, Jenny; Vetharoy, Winston; Guvenel, Aleks; Wawrzyniecka, Patrycja A., 0000-0002-4209-2834; Mekkaoui, Leila, 0000-0001-8640-840X; Cheung, Gordon Weng-Kit; Pinner, Danielle; Chu, Jan; Lucchini, Giovanna; Silva, Juliana; Ciocarlie, Oana; Lazareva, Arina; Inglott, Sarah; Gilmour, Kimberly C.; Ahsan, Gulrukh; Ferrari, Mathieu, 0000-0001-8535-7348; Manzoor, Somayya; Champion, Kim; Brooks, Tony; Lopes, Andre; Hackshaw, Allan; Farzaneh, Farzin; Chiesa, Robert; Rao, Kanchan; Bonney, Denise; Samarasinghe, Sujith; Goulden, Nicholas; Vora, Ajay; Veys, Paul; Hough, Rachael; Wynn, Robert; Pule, Martin A., 0000-0002-8347-9867; Amrolia, Persis J., 0000-0003-0480-3911 | Nature Medicine | 2019 | NA |
| 10.1038/s41591-019-0734-6 | Peripheral Cd8+ T Cell Characteristics Associated With Durable Responses To Immune Checkpoint Blockade In Patients With Metastatic Melanoma | Fairfax, Benjamin P., 0000-0001-7413-5002; Taylor, Chelsea A.; Watson, Robert A.; Nassiri, Isar; Danielli, Sara; Fang, Hai, 0000-0003-3961-8572; Mahe, Elise A.; Cooper, Rosalin; Woodcock, Victoria, 0000-0001-7656-728X; Traill, Zoe; Al-Mossawi, M. Hussein, 0000-0002-2312-3754; Knight, Julian C., 0000-0002-0377-5536; Klenerman, Paul; Payne, Miranda; Middleton, Mark R., 0000-0003-0167-1685 | Nature Medicine | 2020 | NA |
| 10.1038/s41591-019-0737-3 | Safety And Feasibility Of Anti-Cd19 Car T Cells With Fully Human Binding Domains In Patients With B-Cell Lymphoma | Brudno, Jennifer N.; Lam, Norris; Vanasse, Danielle; Shen, Yueh-Wei; Rose, Jeremy J.; Rossi, John; Xue, Allen; Bot, Adrian; Scholler, Nathalie, 0000-0003-3743-7102; Mikkilineni, Lekha; Roschewski, Mark; Dean, Robert; Cachau, Raul, 0000-0001-9260-2102; Youkharibache, Philippe; Patel, Rashmika; Hansen, Brenna; Stroncek, David F.; Rosenberg, Steven A.; Gress, Ronald E.; Kochenderfer, James N., 0000-0002-4362-9875 | Nature Medicine | 2020 | NA |
| 10.1073/pnas.1903520116 | Epigenetic Signature Of Pd-1+ Tcf1+ Cd8 T Cells That Act As Resource Cells During Chronic Viral Infection And Respond To Pd-1 Blockade | Jadhav, Rohit R.; Im, Se Jin; Hu, Bin; Hashimoto, Masao; Li, Peng; Lin, Jian-Xin; Leonard, Warren J.; Greenleaf, William J., 0000-0003-1409-3095; Ahmed, Rafi; Goronzy, Jorg J. | Proceedings Of The National Academy Of Sciences | 2019 | NA |
| 10.1073/pnas.1905675116 | Tox And Tox2 Transcription Factors Cooperate With Nr4A Transcription Factors To Impose Cd8+ T Cell Exhaustion | Seo, Hyungseok, 0000-0002-6632-1208; Chen, Joyce; Gonzalez-Avalos, Edahi; Samaniego-Castruita, Daniela; Das, Arundhoti; Wang, Yueqiang H.; Lopez-Moyado, Isaac F.; Georges, Romain O.; Zhang, Wade; Onodera, Atsushi; Wu, Cheng-Jang, 0000-0002-7640-5915; Lu, Li-Fan; Hogan, Patrick G.; Bhandoola, Avinash, 0000-0002-4657-8372; Rao, Anjana, 0000-0002-1870-1775 | Proceedings Of The National Academy Of Sciences | 2019 | TRUE |
| 10.1084/jem.20180684 | High-Dimensional Single Cell Analysis Identifies Stem-Like Cytotoxic Cd8+ T Cells Infiltrating Human Tumors | Brummelman, Jolanda, 0000-0003-3581-4816; Mazza, Emilia M.C.; Alvisi, Giorgia; Colombo, Federico S., 0000-0003-4480-3481; Grilli, Andrea, 0000-0002-6219-0714; Mikulak, Joanna; Mavilio, Domenico, 0000-0001-6147-0952; Alloisio, Marco; Ferrari, Francesco; Lopci, Egesta; Novellis, Pierluigi; Veronesi, Giulia; Lugli, Enrico, 0000-0002-1964-7678 | Journal Of Experimental Medicine | 2018 | NA |
| 10.1084/jem.20181365 | Cd4+ Resident Memory T Cells Dominate Immunosurveillance And Orchestrate Local Recall Responses | Beura, Lalit K., 0000-0002-8597-3949; Fares-Frederickson, Nancy J.; Steinert, Elizabeth M., 0000-0002-6947-2271; Scott, Milcah C.; Thompson, Emily A.; Fraser, Kathryn A.; Schenkel, Jason M., 0000-0003-4641-6872; Vezys, Vaiva, 0000-0002-2520-809X; Masopust, David, 0000-0002-9440-3884 | Journal Of Experimental Medicine | 2019 | NA |
| 10.1084/jem.20190249 | Single-Cell Transcriptomic Analysis Of Tissue-Resident Memory T Cells In Human Lung Cancer | Clarke, James; Panwar, Bharat; Madrigal, Ariel; Singh, Divya; Gujar, Ravindra; Wood, Oliver; Chee, Serena J.; Eschweiler, Simon; King, Emma V.; Awad, Amiera S.; Hanley, Christopher J., 0000-0003-3816-7220; Mccann, Katy J.; Bhattacharyya, Sourya; Woo, Edwin; Alzetani, Aiman; Seumois, Gregory, 0000-0002-8164-6852; Thomas, Gareth J.; Ganesan, Anusha-Preethi; Friedmann, Peter S.; Sanchez-Elsner, Tilman, 0000-0003-1915-2410; Ay, Ferhat, 0000-0002-0708-6914; Ottensmeier, Christian H., 0000-0003-3619-1657; Vijayanand, Pandurangan, 0000-0001-7067-9723 | Journal Of Experimental Medicine | 2019 | NA |
| 10.1089/hum.2017.234 | Nucleofection With Plasmid Dna For Crispr/Cas9-Mediated Inactivation Of Programmed Cell Death Protein 1 In Cd133-Specific Car T Cells | Hu, Bian; Zou, Yan; Zhang, Linlin; Tang, Jiaxing; Niedermann, Gabriele; Firat, Elke; Huang, Xingxu; Zhu, Xuekai | Human Gene Therapy | 2019 | NA |
| 10.1126/science.aav5728 | Mani, Vinidhra, 0000-0002-1689-8391; Bromley, Shannon K., 0000-0002-5400-896X; Aijo, Tarmo, 0000-0002-3008-4634; Mora-Buch, Rut, 0000-0002-0117-0007; Carrizosa, Esteban; Warner, Ross D., 0000-0001-9394-0912; Hamze, Moustafa, 0000-0002-3117-1967; Sen, Debattama R., 0000-0002-0947-8284; Chasse, Alexandra Y., 0000-0001-7970-2053; Lorant, Alina, 0000-0002-1201-1618; Griffith, Jason W., 0000-0002-8942-0380; Rahimi, Rod A., 0000-0002-7929-2899; Mcentee, Craig P., 0000-0002-4762-7607; Jeffrey, Kate L., 0000-0001-5746-0153; Marangoni, Francesco, 0000-0002-2490-849X; Travis, Mark A.; Lacy-Hulbert, Adam; Luster, Andrew D., 0000-0001-9679-7912; Mempel, Thorsten R., 0000-0001-8635-5424 | Science | 2019 | NA | |
| 10.1126/sciimmunol.aas9673 | Location, Location, Location: Tissue Resident Memory T Cells In Mice And Humans | Szabo, Peter A., 0000-0003-1603-761X; Miron, Michelle, 0000-0002-2593-3857; Farber, Donna L., 0000-0001-8236-9183 | Science Immunology | 2019 | NA |
| 10.1126/sciimmunol.aav5581 | Generation And Persistence Of Human Tissue-Resident Memory T Cells In Lung Transplantation | Science Immunology | 2019 | NA | |
| 10.1126/sciimmunol.aav8995 | Human Cd4 + Cd103 + Cutaneous Resident Memory T Cells Are Found In The Circulation Of Healthy Individuals | Klicznik, Maria M., 0000-0002-3871-5859; Morawski, Peter A., 0000-0001-9159-4032; Hollbacher, Barbara, 0000-0001-9848-7870; Varkhande, Suraj R., 0000-0001-8813-0907; Motley, Samantha J., 0000-0001-6966-9931; Kuri-Cervantes, Leticia, 0000-0002-2432-9500; Goodwin, Eileen; Rosenblum, Michael D., 0000-0002-0462-5732; Long, S. Alice, 0000-0002-0281-1240; Brachtl, Gabriele; Duhen, Thomas; Betts, Michael R.; Campbell, Daniel J., 0000-0002-9652-7178; Gratz, Iris K., 0000-0001-7470-7277 | Science Immunology | 2019 | NA |
| 10.1126/sciimmunol.aay0555 | Vegf-A Drives Tox-Dependent T Cell Exhaustion In Anti<U+2013>Pd-1<U+2013>Resistant Microsatellite Stable Colorectal Cancers | Kim, Chang Gon, 0000-0001-8034-3174; Jang, Mi, 0000-0002-0153-9847; Kim, Youngun, 0000-0003-0264-5446; Leem, Galam; Kim, Kyung Hwan, 0000-0002-6713-1350; Lee, Hoyoung, 0000-0001-9917-8834; Kim, Tae-Shin, 0000-0003-4736-0727; Choi, Seong Jin; Kim, Hyung-Don; Han, Ji Won; Kwon, Minsuk, 0000-0003-1833-6576; Kim, Jong Hoon, 0000-0002-3385-8180; Lee, Andrew J.; Nam, Su Kyung, 0000-0001-6926-0968; Bae, Seok-Joo, 0000-0002-0473-2503; Lee, Sat Byol; Shin, Sang Joon, 0000-0001-5350-7241; Park, Sung Ho, 0000-0003-4856-7287; Ahn, Joong Bae; Jung, Inkyung, 0000-0002-5885-2754; Lee, Kang Young, 0000-0001-5944-2063; Park, Su-Hyung, 0000-0001-6363-7736; Kim, Hoguen, 0000-0002-7444-2771; Min, Byung Soh, 0000-0003-0180-8565; Shin, Eui-Cheol, 0000-0002-6308-9503 | Science Immunology | 2019 | NA |
| 10.1126/scisignal.aat6753 | Phosphoproteomic Analysis Of Chimeric Antigen Receptor Signaling Reveals Kinetic And Quantitative Differences That Affect Cell Function | Salter, Alexander I., 0000-0003-3820-0895; Ivey, Richard G.; Kennedy, Jacob J.; Voillet, Valentin; Rajan, Anusha, 0000-0002-0036-4301; Alderman, Eva J.; Voytovich, Uliana J., 0000-0002-7235-1577; Lin, Chenwei; Sommermeyer, Daniel; Liu, Lingfeng; Whiteaker, Jeffrey R., 0000-0001-5042-8580; Gottardo, Raphael, 0000-0002-3867-0232; Paulovich, Amanda G.; Riddell, Stanley R., 0000-0002-4688-9920 | Science Signaling | 2018 | NA |
| 10.1126/scitranslmed.aau5907 | The Tyrosine Kinase Inhibitor Dasatinib Acts As A Pharmacologic On/Off Switch For Car T Cells | Mestermann, Katrin, 0000-0002-3585-5055; Giavridis, Theodoros; Weber, Justus; Rydzek, Julian; Frenz, Silke, 0000-0002-2026-2177; Nerreter, Thomas, 0000-0002-0493-1369; Mades, Andreas, 0000-0001-7322-2817; Sadelain, Michel, 0000-0002-9031-8025; Einsele, Hermann; Hudecek, Michael, 0000-0002-2280-2202 | Science Translational Medicine | 2019 | NA |
| 10.1146/annurev-immunol-041015-055318 | Cd8 T Cell Exhaustion During Chronic Viral Infection And Cancer | Mclane, Laura M.; Abdel-Hakeem, Mohamed S.; Wherry, E. John | Annual Review Of Immunology | 2019 | NA |
| 10.1146/annurev-immunol-042617-053214 | Tissue-Resident T Cells And Other Resident Leukocytes | Masopust, David; Soerens, Andrew G. | Annual Review Of Immunology | 2019 | NA |
| 10.1158/1078-0432.ccr-18-3784 | Modulation Of Target Antigen Density Improves Car T-Cell Functionality And Persistence | Ramakrishna, Sneha, 0000-0001-7445-3190; Highfill, Steven L.; Walsh, Zachary; Nguyen, Sang M.; Lei, Haiyan; Shern, Jack F., 0000-0001-5579-7625; Qin, Haiying, 0000-0001-5966-8812; Kraft, Ira L.; Stetler-Stevenson, Maryalice; Yuan, Constance M., 0000-0002-2601-3665; Hwang, Jennifer D.; Feng, Yang; Zhu, Zhongyu; Dimitrov, Dimiter; Shah, Nirali N.; Fry, Terry J. | Clinical Cancer Research | 2019 | NA |
| 10.1158/2159-8290.cd-19-0945 | Tuning The Antigen Density Requirement For Car T-Cell Activity | Majzner, Robbie G.; Rietberg, Skyler P.; Sotillo, Elena; Dong, Rui, 0000-0002-9118-3636; Vachharajani, Vipul T.; Labanieh, Louai, 0000-0003-3998-7415; Myklebust, June H.; Kadapakkam, Meena; Weber, Evan W.; Tousley, Aidan M.; Richards, Rebecca M.; Heitzeneder, Sabine; Nguyen, Sang M.; Wiebking, Volker, 0000-0002-9429-5254; Theruvath, Johanna; Lynn, Rachel C.; Xu, Peng; Dunn, Alexander R.; Vale, Ronald D.; Mackall, Crystal L., 0000-0003-0359-9023 | Cancer Discovery | 2020 | NA |
| 10.1158/2326-6066.cir-18-0466 | Il15 Enhances Car-T Cell Antitumor Activity By Reducing Mtorc1 Activity And Preserving Their Stem Cell Memory Phenotype | Alizadeh, Darya; Wong, Robyn A.; Yang, Xin; Wang, Dongrui; Pecoraro, Joseph R.; Kuo, Cheng-Fu; Aguilar, Brenda; Qi, Yue; Ann, David K.; Starr, Renate; Urak, Ryan; Wang, Xiuli; Forman, Stephen J.; Brown, Christine E. | Cancer Immunology Research | 2019 | NA |
| 10.1172/jci.insight.133977 | Tang, Na; Cheng, Chen; Zhang, Xingying; Qiao, Miaomiao; Li, Na; Mu, Wei; Wei, Xiao-Fei, 0000-0001-6775-346X; Han, Weidong; Wang, Haoyi | Jci Insight | 2020 | NA | |
| 10.1172/jci133215 | Single Residue In Cd28-Costimulated Car-T Cells Limits Long-Term Persistence And Antitumor Durability | Guedan, Sonia, 0000-0002-9605-0760; Madar, Aviv; Casado-Medrano, Victoria; Shaw, Carolyn; Wing, Anna; Liu, Fang; Young, Regina M.; June, Carl H., 0000-0003-0241-3557; Posey, Avery D., 0000-0001-8711-629X | Journal Of Clinical Investigation | 2020 | NA |
| 10.1186/s40425-019-0806-7 | Crispr-Cas9 Disruption Of Pd-1 Enhances Activity Of Universal Egfrviii Car T Cells In A Preclinical Model Of Human Glioblastoma | Choi, Bryan D.; Yu, Xiaoling; Castano, Ana P.; Darr, Henia; Henderson, Daniel B.; Bouffard, Amanda A.; Larson, Rebecca C.; Scarfo, Irene; Bailey, Stefanie R.; Gerhard, Genevieve M.; Frigault, Matthew J.; Leick, Mark B.; Schmidts, Andrea; Sagert, Jason G.; Curry, William T.; Carter, Bob S.; Maus, Marcela V., 0000-0002-7578-0393 | Journal For Immunotherapy Of Cancer | 2019 | NA |
| 10.4049/jimmunol.1900052 | The Functional Requirement For Cd69 In Establishment Of Resident Memory Cd8+T Cells Varies With Tissue Location | Walsh, Daniel A.; Borges Da Silva, Henrique, 0000-0002-5021-6200; Beura, Lalit K., 0000-0002-8597-3949; Peng, Changwei, 0000-0002-0710-9573; Hamilton, Sara E.; Masopust, David; Jameson, Stephen C., 0000-0001-9137-1146 | The Journal Of Immunology | 2019 | NA |